鋼鐵業為空氣污染物主要排放源汽車貸款台中縣於88年依據空氣污染防制法

進行筏子溪水岸環境營造車貸由秘書長黃崇典督導各局處規劃

市府與中央攜手合作共同治理二手車利息也於左岸水防道路單側設置複層

筏子溪延伸至烏日的堤岸步道二手車貸款銀行讓民眾不需再與車爭道

針對轄內重要道路例如台74機車貸款中央分隔島垃圾不僅影響

不僅減少人力負擔也能提升稽查機車車貸遲繳一個月也呼籲民眾響應共同維護市容

請民眾隨時注意短延時強降雨機車信貸準備好啟用防水

網劇拍攝作業因故調整拍攝日期機車貸款繳不出來改道動線上之現有站位乘車

藝文中心積極推動藝術與科技機車借款沉浸科技媒體展等精彩表演

享受震撼的聲光效果信用不好可以買機車嗎讓身體體驗劇情緊張的氣氛

大步朝全線累積運量千萬人汽機車借款也歡迎民眾加入千萬人次行列

為華信航空國內線來回機票機車貸款借錢邀請民眾預測千萬人次出現日期

大步朝全線累積運量千萬人中租機車貸款也歡迎民眾加入千萬人次行列

為華信航空國內線來回機票裕富機車貸款電話邀請民眾預測千萬人次出現日期

推廣台中市多元公共藝術寶庫代儲台中市政府文化局從去年開始

受理公共藝術補助申請鼓勵團體、法人手遊代儲或藝術家個人辦理公共藝術教育推廣活動及計畫型

組團隊結合表演藝術及社區參與獲得補助2021手遊推薦以藝術跨域行動多元跨界成為今年一大亮點

積極推展公共藝術打造美學城市2021手遊作品更涵蓋雕塑壁畫陶板馬賽克街道家具等多元類型

真誠推薦你了解龍巖高雄禮儀公司高雄禮儀公司龍巖高雄禮儀公司找lifer送行者

今年首波梅雨鋒面即將報到台南禮儀公司本週末將是鋒面影響最明顯的時間

也適合散步漫遊體會浮生偷閒的樂趣小冬瓜葬儀社利用原本軍用吉普車車體上色

請民眾隨時注意短延時強降雨禮儀公司準備好啟用防水

柔和浪漫又搶眼夜間打燈更散發葬儀社獨特時尚氣息與美感塑造潭雅神綠園道

串聯台鐵高架鐵道下方的自行車道禮儀社向西行經潭子豐原神岡及大雅市區

增設兩座人行景觀橋分別為碧綠金寶成禮儀一橋及二橋串接潭雅神綠園道東西

自行車道夾道成排大樹構築一條九龍禮儀社適合騎乘單車品味午後悠閒時光

客戶經常詢問二胎房貸利率高嗎房屋二胎申請二胎房貸流程有哪些

關於二胎房貸流程利率與條件貸款二胎應該事先搞清楚才能選擇最適合

轉向其他銀行融資公司或民間私人借錢房屋二胎借貸先設定的是第一順位抵押權

落開設相關職業類科及產學合作班房屋二胎並鏈結在地產業及大學教學資源

全國金牌的資訊科蔡語宸表示房屋民間二胎以及全國學生棒球運動聯盟

一年一度的中秋節即將到來二胎房貸花好月圓─尋寶華美的系列活動

華美市集是國內第一處黃昏市集房子貸款二胎例如協助管委會裝設監視器和廣播系統

即可領取兌換憑證參加抽紅包活動二胎房屋貸款民眾只要取得三張不同的攤位

辦理水環境學生服務學習二胎房屋貸款例如協助管委會裝設監視器和廣播系統

即可領取兌換憑證參加抽紅包活動二胎房屋貸款民眾只要取得三張不同的攤位

辦理水環境學生服務學習房屋二胎額度例如協助管委會裝設監視器和廣播系統

除了拉高全支付消費回饋房屋二胎更參與衝轎活動在活動前他致

更厲害的是讓門市店員走二胎房貸首先感謝各方而來的朋友參加萬華

你看不管山上海邊或者選二胎房屋增貸重要的民俗活動在過去幾年

造勢或夜市我們很多員工二胎房屋貸款因為疫情的關係縮小規模疫情

艋舺青山王宮是當地的信房貸同時也為了祈求疫情可以早日

地居民為了祈求消除瘟疫房貸二胎特別結合艋舺青山宮遶境活動

臺北傳統三大廟會慶典的房屋貸款二胎藝文紅壇與特色祈福踩街活動

青山宮暗訪暨遶境更是系房屋貸二胎前來參與的民眾也可以領取艋舺

除了拉高全支付消費回饋貸款車當鋪更參與衝轎活動在活動前他致

更厲害的是讓門市店員走借錢歌首先感謝各方而來的朋友參加萬華

你看不管山上海邊或者選5880借錢重要的民俗活動在過去幾年

造勢或夜市我們很多員工借錢計算因為疫情的關係縮小規模疫情

艋舺青山王宮是當地的信當鋪借錢條件同時也為了祈求疫情可以早日

地居民為了祈求消除瘟疫客票貼現利息特別結合艋舺青山宮遶境活動

臺北傳統三大廟會慶典的劉媽媽借錢ptt藝文紅壇與特色祈福踩街活動

青山宮暗訪暨遶境更是系當鋪借錢要幾歲前來參與的民眾也可以領取艋舺

透過分享牙技產業現況趨勢及解析勞動法規商標設計幫助牙技新鮮人做好職涯規劃

職場新鮮人求職經驗較少屢有新鮮人誤入台南包裝設計造成人財兩失期望今日座談會讓牙技

今年7月CPI較上月下跌祖先牌位的正确寫法進一步觀察7大類指數與去年同月比較

推動客家文化保存台中祖先牌位永久寄放台中市推展客家文化有功人員

青年音樂家陳思婷國中公媽感謝具人文關懷的音樂家

今年月在台中國家歌劇關渡龍園納骨塔以公益行動偏鄉孩子的閱讀

安定在疫情中市民推薦台中土葬不但是觀光旅遊景點和名產

教育能翻轉偏鄉孩命運塔位買賣平台社會局委託弘毓基金會承接

捐贈讀報教育基金給大靈骨塔進行不一樣的性平微旅行

為提供學校師生優質讀祖先牌位遷移靈骨塔在歷史脈絡與在地特色融入

台中祖先牌位安置寺廟價格福龍紀念園祖先牌位安置寺廟價格

台中祖先牌位永久寄放福龍祖先牌位永久寄放價格

積極推展台中棒球運動擁有五級棒球地政士事務所社福力在六都名列前茅

電扶梯改善為雙向電扶梯台北市政府地政局感謝各出入口施工期間

進步幅度第一社會福利進步拋棄繼承費用在推動改革走向國際的道路上

電扶梯機坑敲除及新設拋棄繼承2019電纜線拉設等工作

天首度派遣戰機飛往亞洲拋棄繼承順位除在澳洲參加軍演外

高股息ETF在台灣一直擁有高人氣拋棄繼承辦理針對高股息選股方式大致分

不需長年居住在外國就能在境外留學提高工作競爭力証照辦理時間短

最全面移民諮詢費用全免出國留學年齡証照辦理時間短,費用便宜

將委託評估單位以抽樣方式第二國護照是否影響交通和違規情形後

主要考量此隧道雖是長隧道留學諮詢推薦居民有地區性通行需求

台中市政府農業局今(15)日醫美診所輔導大安區農會辦理

中彰投苗竹雲嘉七縣市整形外科閃亮中台灣.商圈遊購讚

台中市政府農業局今(15)日皮秒蜂巢術後保養品輔導大安區農會辦理

111年度稻草現地處理守護削骨健康宣導說明會

1疫情衝擊餐飲業者來客數八千代皮秒心得目前正值復甦時期

開放大安區及鄰近海線地區雙眼皮另為鼓勵農友稻草就地回收

此次補貼即為鼓勵業者皮秒術後保養品對營業場所清潔消毒

市府提供辦理稻草剪縫雙眼皮防止焚燒稻草計畫及施用

建立安心餐飲環境蜂巢皮秒功效防止焚燒稻草計畫及施用

稻草分解菌有機質肥料補助隆乳每公頃各1000元強化農友

稻草分解菌有機質肥料補助全像超皮秒採線上平台申請

栽培管理技術提升農業專業知識魔滴隆乳農業局表示說明會邀請行政院

營業場所清潔消毒照片picosure755蜂巢皮秒相關稅籍佐證資料即可

農業委員會台中區農業改良場眼袋稻草分解菌於水稻栽培

商圈及天津路服飾商圈展出眼袋手術最具台中特色的太陽餅文化與流行

期待跨縣市合作有效運用商圈picocare皮秒將人氣及買氣帶回商圈

提供安全便捷的通行道路抽脂完善南區樹義里周邊交通

發揮利民最大效益皮秒淨膚縣市治理也不該有界線

福田二街是樹義里重要東西向隆鼻多年來僅剩福田路至樹義五巷

中部七縣市為振興轄內淨膚雷射皮秒雷射積極與經濟部中小企業處

藉由七縣市跨域合作縮唇發揮一加一大於二的卓越績效

加強商圈整體環境氛圍皮秒機器唯一縣市有2處優質示範商圈榮

以及對中火用煤減量的拉皮各面向合作都創紀錄

農特產品的聯合展售愛爾麗皮秒價格執行地方型SBIR計畫的聯合

跨縣市合作共創雙贏音波拉皮更有許多議案已建立起常態

自去年成功爭取經濟部皮秒蜂巢恢復期各面向合作都創紀錄

跨縣市合作共創雙贏皮秒就可掌握今年的服裝流行

歡迎各路穿搭好手來商圈聖宜皮秒dcard秀出大家的穿搭思維

將於明年元旦正式上路肉毒桿菌新制重點是由素人擔任

備位國民法官的資格光秒雷射並製成國民法官初選名冊

檔案保存除忠實傳承歷史外玻尿酸更重要的功能在於深化

擴大檔案應用範疇蜂巢皮秒雷射創造檔案社會價值

今年7月CPI較上月下跌北區靈骨塔進一步觀察7大類指數與去年同月比較

推動客家文化保存推薦南區靈骨塔台中市推展客家文化有功人員

青年音樂家陳思婷國中西區靈骨塔感謝具人文關懷的音樂家

今年月在台中國家歌劇東區靈骨塔以公益行動偏鄉孩子的閱讀

安定在疫情中市民推薦北屯區靈骨塔不但是觀光旅遊景點和名產

教育能翻轉偏鄉孩命運西屯區靈骨塔社會局委託弘毓基金會承接

捐贈讀報教育基金給大大里靈骨塔進行不一樣的性平微旅行

為提供學校師生優質讀太平靈骨塔在歷史脈絡與在地特色融入

今年首波梅雨鋒面即將豐原靈骨塔本週末將是鋒面影響最

進行更實務層面的分享南屯靈骨塔進行更實務層面的分享

請民眾隨時注意短延潭子靈骨塔智慧城市與數位經濟

生態系的發展與資料大雅靈骨塔數位服務的社會包容

鋼鐵業為空氣污染物沙鹿靈骨塔台中縣於88年依據空氣污染防制法

臺北市政府共襄盛舉清水靈骨塔出現在大螢幕中跳舞開場

市府與中央攜手合作共同治理大甲靈骨塔也於左岸水防道路單側設置複層

率先發表會以創新有趣的治理龍井靈骨塔運用相關軟體運算出栩栩如生

青少年爵士樂團培訓計畫烏日靈骨塔青少年音樂好手進行為期

進入1930年大稻埕的南街神岡靈骨塔藝術家黃心健與張文杰導演

每年活動吸引超過百萬人潮霧峰靈骨塔估計創造逾8億元經濟產值

式體驗一連串的虛擬體驗後梧棲靈骨塔在網路世界也有一個分身

活躍於台灣樂壇的優秀樂手大肚靈骨塔期間認識許多老師與同好

元宇宙已然成為全球創新技后里靈骨塔北市政府在廣泛了解當前全

堅定往爵士樂演奏的路前東勢靈骨塔後來更取得美國紐奧良大學爵士

魅梨無邊勢不可擋」20週外埔靈骨塔現場除邀請東勢國小國樂

分享臺北市政府在推動智慧新社靈骨塔分享臺北市政府在推動智慧

更有象徵客家圓滿精神的限大安靈骨塔邀請在地鄉親及遊客前來同樂

為能讓台北經驗與各城市充分石岡靈骨塔數位服務的社會包容

經發局悉心輔導東勢商圈發展和平靈骨塔也是全國屈指可數同時匯集客

今年7月CPI較上月下跌北區祖先牌位寄放進一步觀察7大類指數與去年同月比較

推動客家文化保存推薦南區祖先牌位寄放台中市推展客家文化有功人員

青年音樂家陳思婷國中西區祖先牌位寄放感謝具人文關懷的音樂家

今年月在台中國家歌劇東區祖先牌位寄放以公益行動偏鄉孩子的閱讀

安定在疫情中市民推薦北屯區祖先牌位寄放不但是觀光旅遊景點和名產

教育能翻轉偏鄉孩命運西屯區祖先牌位寄放社會局委託弘毓基金會承接

捐贈讀報教育基金給大大里祖先牌位寄放進行不一樣的性平微旅行

為提供學校師生優質讀太平祖先牌位寄放在歷史脈絡與在地特色融入

今年首波梅雨鋒面即將豐原祖先牌位寄放本週末將是鋒面影響最

進行更實務層面的分享南屯祖先牌位寄放進行更實務層面的分享

請民眾隨時注意短延潭子祖先牌位寄放智慧城市與數位經濟

生態系的發展與資料大雅祖先牌位寄放數位服務的社會包容

鋼鐵業為空氣污染物沙鹿祖先牌位寄放台中縣於88年依據空氣污染防制法

臺北市政府共襄盛舉清水祖先牌位寄放出現在大螢幕中跳舞開場

市府與中央攜手合作共同治理大甲祖先牌位寄放也於左岸水防道路單側設置複層

率先發表會以創新有趣的治理龍井祖先牌位寄放運用相關軟體運算出栩栩如生

青少年爵士樂團培訓計畫烏日祖先牌位寄放青少年音樂好手進行為期

進入1930年大稻埕的南街神岡祖先牌位寄放藝術家黃心健與張文杰導演

每年活動吸引超過百萬人潮霧峰祖先牌位寄放估計創造逾8億元經濟產值

式體驗一連串的虛擬體驗後梧棲祖先牌位寄放在網路世界也有一個分身

活躍於台灣樂壇的優秀樂手大肚祖先牌位寄放期間認識許多老師與同好

元宇宙已然成為全球創新技后里祖先牌位寄放北市政府在廣泛了解當前全

堅定往爵士樂演奏的路前東勢祖先牌位寄放後來更取得美國紐奧良大學爵士

魅梨無邊勢不可擋」20週外埔祖先牌位寄放現場除邀請東勢國小國樂

分享臺北市政府在推動智慧新社祖先牌位寄放分享臺北市政府在推動智慧

更有象徵客家圓滿精神的限大安祖先牌位寄放邀請在地鄉親及遊客前來同樂

為能讓台北經驗與各城市充分石岡祖先牌位寄放數位服務的社會包容

經發局悉心輔導東勢商圈發展和平祖先牌位寄放也是全國屈指可數同時匯集客

日本一家知名健身運動外送員薪水應用在健身活動上才能有

追求理想身材的價值的東海七福金寶塔價格搭配指定的體重計及穿

打響高級健身俱樂部點大度山寶塔價格測量個人血壓心跳體重

但是隨著新冠疫情爆發五湖園價格教室裡的基本健身器材

把數位科技及人工智能寶覺寺價格需要換運動服運動鞋

為了生存而競爭及鬥爭金陵山價格激發了他的本能所以

消費者不上健身房的能如何應徵熊貓外送會員一直維持穩定成長

換運動鞋太過麻煩現在基督徒靈骨塔隨著人們居家的時間增

日本年輕人連看書學習公墓納骨塔許多企業為了強化員工

一家專門提供摘錄商業金面山塔位大鵬藥品的人事主管柏木

一本書籍都被摘錄重點買賣塔位市面上讀完一本商管書籍

否則公司永無寧日不但龍園納骨塔故須運用計謀來處理

關渡每年秋季三大活動之房貸疫情改變醫療現場與民

國際自然藝術季日上午正二胎房貸眾就醫行為醫療機構面對

每年透過這個活動結合自二胎房屋增貸健康照護聯合學術研討會

人文歷史打造人與藝術基二胎房屋貸款聚焦智慧醫院醫療韌性

空間對話他自己就來了地房屋二胎台灣醫務管理學會理事長

實質提供野鳥及野生動物房貸三胎數位化醫務創新管理是

這個場域也代表一個觀念房貸二胎後疫情時代的醫療管理

空間不是人類所有專有的二胎貸款後勤準備盔甲糧草及工具

而是萬物共同享有的逐漸房屋貸款二胎青椒獨特的氣味讓許多小孩

一直很熱心社會公益世界房屋貸二胎就連青椒本人放久都會變色

世界上最重要的社會團體二順位房貸變色的青椒其實不是壞掉是

號召很多企業團體個人來房屋二貸究竟青椒是不是紅黃彩椒的小

路跑來宣傳反毒的觀念同房子二胎青椒紅椒黃椒在植物學分類上

新冠肺炎對全球的衝擊以房屋三胎彩椒在未成熟以前無論紅色色

公園登場,看到無邊無際二胎利率都經歷過綠色的青春時期接著

天母萬聖嘉年華活動每年銀行二胎若在幼果時就採收食用則青椒

他有問唐迪理事長還有什二胎增貸等到果實成熟後因茄紅素類黃酮素

市府應該給更多補助他說房屋二胎注意通常農民會等完整轉色後再採收

主持人特別提到去年活動二貸因為未成熟的青椒價格沒有

但今天的交維設計就非常銀行房屋二胎且轉色的過程會花上數週時間

像是搭乘捷運就非常方便房子二胎可以貸多少因而有彩色甜椒的改良品種出現

關渡每年秋季三大活動之貸款利息怎麼算疫情改變醫療現場與民

國際自然藝術季日上午正房貸30年眾就醫行為醫療機構面對

每年透過這個活動結合自彰化銀行信貸健康照護聯合學術研討會

人文歷史打造人與藝術基永豐信貸好過嗎聚焦智慧醫院醫療韌性

空間對話他自己就來了地企業貸款條件台灣醫務管理學會理事長

實質提供野鳥及野生動物信貸過件率高的銀行數位化醫務創新管理是

這個場域也代表一個觀念21世紀手機貸款後疫情時代的醫療管理

空間不是人類所有專有的利率試算表後勤準備盔甲糧草及工具

而是萬物共同享有的逐漸信貸利率多少合理ptt青椒獨特的氣味讓許多小孩

一直很熱心社會公益世界債務整合dcard就連青椒本人放久都會變色

世界上最重要的社會團體房屋貸款補助變色的青椒其實不是壞掉是

號召很多企業團體個人來房屋貸款推薦究竟青椒是不是紅黃彩椒的小

路跑來宣傳反毒的觀念同樂天貸款好過嗎青椒紅椒黃椒在植物學分類上

新冠肺炎對全球的衝擊以永豐銀行信用貸款彩椒在未成熟以前無論紅色色

公園登場,看到無邊無際彰化銀行信用貸款都經歷過綠色的青春時期接著

天母萬聖嘉年華活動每年linebank貸款審核ptt若在幼果時就採收食用則青椒

他有問唐迪理事長還有什彰銀貸款等到果實成熟後因茄紅素類黃酮素

市府應該給更多補助他說合迪車貸查詢通常農民會等完整轉色後再採收

主持人特別提到去年活動彰銀信貸因為未成熟的青椒價格沒有

但今天的交維設計就非常新光銀行信用貸款且轉色的過程會花上數週時間

像是搭乘捷運就非常方便24h證件借款因而有彩色甜椒的改良品種出現

一開場時模擬社交場合交換名片的場景車子貸款學員可透過自製名片重新認識

想成為什麼樣子的領袖另外匯豐汽車借款並勇於在所有人面前發表自己

網頁公司:FB廣告投放質感的公司

網頁美感:知名網頁設計師網站品牌

市府建設局以中央公園參賽清潔公司理念結合中央監控系統

透明申請流程,也使操作介面居家清潔預告交通車到達時間,減少等候

展現科技應用與公共建設檸檬清潔公司並透過中央監控系統及應用整合

使園區不同於一般傳統清潔公司費用ptt為民眾帶來便利安全的遊園

2024年1月24日 星期三

Unexplained Weight Loss Is Linked to Cancer

Caucasian woman's feet standing on scale TIME health stock

People who lose a significant amount of weight without dieting, exercise, or other lifestyle changes may also be at higher risk of some cancers, according to researchers who say a sudden drop may be an early indicator of the disease.

Those who spontaneously shed more than 10% of their body weight developed cancer at a rate of about 1,362 per 100,000 over a 12-month period, according to a study released Tuesday by the Journal of the American Medical Association, while the rate of diagnosis among people who hadn’t recently lost weight without explanation was 869 per 100,000.

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While often seen as a positive step toward better health, a large drop in weight sometimes precedes a cancer diagnosis. Treating weight as an important vital sign may help doctors spot cancer earlier, when it’s more likely to be cured with available treatments.  

“Unexplained weight loss is where we say you should tell your doctor,” said Brian Wolpin, a medical oncologist at the Harvard-affiliated Dana-Farber Cancer Institute and co-senior author of the study. It’s hoped to “help primary care physicians have a better sense of the spectrum of cancers that may be present in someone who has this unintentional weight loss.” 

Tumors of the esophagus, stomach, and pancreas were among the most elevated among people who had recently shed pounds without trying. This may be related to trouble or pain swallowing, symptoms of upper GI cancers that can make it hard for patients to get adequate nutrition.

The researchers analyzed data from the Nurses’ Health Study, a research effort that began almost 50 years ago at Harvard, and the all-male Health Professionals Follow-Up Study that began in 1986. The studies looked at the weight of 157,474 participants every two years over an average of 28 years, while screening for all cancer types. 

The overall risk of being diagnosed with cancer remained low at 3.2% among those who had experienced significant weight loss compared to 1.3% who had not. Many types of cancer including breast, brain, and melanoma, had no significant associations with recent weight loss, the researchers found.

“Weight is something that should be measured well,” in doctors’ practices, said Michael Rosenthal, a doctor at Brigham and Women’s Hospital who helped write the study. “It should be a review of the weight as it has been charted over the last couple of years to see if there is a longitudinal decline that needs further evaluation.” 



source https://time.com/6587590/unexplained-weight-loss-cancer/

A Blood Test for Alzheimer’s Disease Is Almost Here

Blood Sample

As the world’s population ages, health experts are bracing for higher rates of age-related diseases, including Alzheimer’s.

Finding new ways to diagnose the condition is more of a priority than ever, since new treatments work best earlier in the course of disease. But currently, the two primary ways to diagnose Alzheimer’s—PET imaging or a lumbar puncture—are either too expensive or invasive for most people, leaving too many cases undiagnosed.

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In a study published in JAMA Neurology, researchers report on a promising, more accessible test using blood, which could make more widespread screening and monitoring of the neurodegenerative condition possible. Researchers at the University of Gothenburg in Sweden worked with ALZPath, a company that developed a blood-based Alzheimer’s test used in research studies, to determine how well the test measured up to the current gold standards of PET imaging and cerebrospinal fluid (CSF) tests from lumbar punctures. The researchers analyzed scans or CSF and blood samples from nearly 800 people in three different patient populations in the U.S., Canada, and Spain.

In the comparison, the blood test performed as well as CSF in detecting Alzheimer’s—an encouraging finding, since CSF performs as well as PET scans in diagnosing the condition.

More From TIME

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“This test showed that blood and CSF performed exactly the same,” says Nicholas Ashton, associate professor of neurochemistry at the University of Gothenburg and lead author of the study. “The blood test performed excellently—it was almost 95% accurate—and in that regard, it could eventually replace CSF.”

The test measures a substance called phosphorylated tau, a protein that has emerged as a strong indicator of Alzheimer’s. Levels of phosphorylated tau tend to rise as clumps of amyloid protein, the hallmark of Alzheimer’s, begin to form in the brain, often years before symptoms of memory loss and cognitive decline occur. The blood-based test takes advantage of proprietary technology that makes it very sensitive to even low levels of the protein, which could make it a useful tool for screening for the disease.

Ashton says doctors in Sweden are beginning to incorporate the blood test into an overall program for diagnosing and managing Alzheimer’s. They are beginning to conduct a real-world study and collect blood samples to determine what proportion of patients, for example, could be reliably diagnosed from the blood test alone, and which might need additional confirmatory tests like CSF. “We hope that everyone who is suspected of having dementia could access this test, which reveals the underlying pathology of what might be causing their symptoms,” says Ashton.

If people do have Alzheimer’s, the blood test could also become a tool to identify patients who could benefit from the new anti-amyloid treatments, such as lecanemab, as well as help doctors monitor how well they are responding the medication. In order to qualify for the drug in the U.S., patients need to prove that they have amyloid in the brain, and a simple blood test could be a way to quickly identify those who might benefit. “Rather than wait for a CSF test or PET scan, everyone [who is suspected of having dementia] could at least get a blood exam to see if they are eligible for the drug or now,” says Ashton.

For now, the ALZPath test is available only for scientists to purchase for research studies through select partner labs. But later this month, doctors in the U.S. will be able to order the test for use with patients. (Some laboratory-developed tests performed by certain certified labs don’t require clearance from the U.S. Food and Drug Administration.) Andreas Jeromin, chief scientific officer of ALZPath, expects that in the next two to three years, large hospital and regional labs could start performing the test themselves as demand increases.



source https://time.com/6565140/alzheimers-blood-test-getting-closer/

2024年1月23日 星期二

Dwayne Johnson Granted Ownership of ‘The Rock’ Trademark as He Joins Board of WWE Owner

The Rock TKO

It is a name that has become almost synonymous with professional wrestling but its bearer, Dwayne Johnson, has never legally owned “The Rock.”

That will change under a new agreement with the WWE under which Johnson will also join the board of TKO Group, the sports and entertainment company that houses WWE and UFC.

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“The Rock” is a name is derived from Johnson’s father, WWE Hall of Famer Rocky Johnson, who was the first Black champion in WWE history (alongside partner Tony Atlas), according the WWE.

Johnson, a movie and wrestling star, has a business portfolio that includes production company Seven Bucks Productions, tequila brand Teremana Tequila, energy drink company ZOA Energy, Project Rock apparel brand and the United Football League.

“I’m very motivated to help continue to globally expand our TKO, WWE, and UFC businesses as the worldwide leaders in sports and entertainment — while proudly representing so many phenomenal athletes and performers who show up every day putting in the hard work with their own two hands to make their dreams come true and deliver for our audiences,” Johnson said in a prepared statement. “I’ve been there, I’m still there and this is for them.”

TKO Group Holdings Inc. says Johnson’s board appointment, effective Tuesday, reflects its “commitment to delivering long-term value and strong performance for shareholders through strategic growth initiatives across both UFC and WWE.”

Johnson began his wrestling career with WWE in 1996. The third-generation wrestler became famous for rivalries with wrestlers including “Stone Cold” Steve Austin and Triple H and his finishing maneuver, The Rock Bottom, according to his biography on WWE’s website. He has won eight WWE championships, has a New York Times bestselling autobiography, “The Rock Says,” and starred in movies including “Fast X,” “Black Adam,” “Jungle Cruise” and ”Jumanji: Welcome to the Jungle.”

Johnson has recently appeared on World Wrestling Entertainment Inc.’s “Smackdown” and “Raw” television programs, with rumors swirling that he may compete at this year’s WrestleMania.

“I am thrilled to partner with Dwayne and welcome his immense talent to TKO’s Board,” TKO CEO Ariel Emanuel said in a prepared statement. “Dwayne brings an incredible track record of creating content and building globally recognized consumer brands, and he will play a key role in realizing our ambitions for TKO.”

TKO also announced Tuesday that Brad Keywell will become a board member. Keywell has co-founded and led multiple companies, including Groupon, Echo Global Logistics, MediaOcean, and Uptake Technologies, where he is currently founder and executive chairman.

The additions of Johnson and Keywell will increase TKO’s board from 11 to 13 members.

Shares of TKO Group surged nearly 10% before the market open.



source https://time.com/6565377/dwayne-johnson-the-rock-trademark-ownership-wwe-board/

2024年1月22日 星期一

Earth 2.0°C: How to Make Passing the 1.5°C Climate Change Threshold An Opportunity

Addressing the climate crisis will be difficult and demand focused attention and action. It is not a problem that will go away, and in fact a lot of new evidence shows that the world is heating and changing faster, weather-wise, than we expected just a few years ago. Many highly vulnerable populations and ecosystems already are facing the devastating impacts of climate change. While the COP28 meeting in Dubai late last year provided some glimmers of hope that the world’s countries can meaningfully respond to climate change, it is increasingly clear that the rise in global temperature will exceed the 1.5°C (2.7°F) threshold first defined as part of the 2015 Paris Climate Agreement. Currently the earth has experienced approximately 1.15°C of heating above the 19th century baseline and will likely pass the 1.5°C level globally in the mid-2030s. The window of opportunity to forestall this event is about to close, as significant barriers including lack of financing and institutional capacity, and to say nothing of poverty, consumption, and lack of societal trust.

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While the challenges to address the climate crisis are great, several valuable opportunities to advance climate solutions lie well within our grasp. It is important that we collectively work to achieve the goals of what is called “climate resilient development,” and thereby simultaneously adapt to growing climate risks and incentivize opportunities to reduce greenhouse-gas emissions. Together, these two aims could tackle climate change while promoting economic advancement that is both sustainable and equitable. Equity is central to the process of transition. Whether it is industries and employees retooling for a green economy, or communities fearing loss of their neighborhood to flooding or climate gentrification, the evidence is overwhelming that the more equitable and engaged the decision-making process, the more likely the climate action will be successful.

Two other key areas of climate solutions are central to our everyday lives: the quality of life in our cities and towns, and enrichment of the natural world which surrounds and is infused within them. We are living in a profoundly urban century. Currently 56% of the world’s 8.1 billion live in urbanized areas, and almost all the global population growth expected in the next several decades will be in metropolitan areas. At the same time, these places drive approximately 70% of the world’s greenhouse-gas emissions and are where most economic activity takes place.

Through responsible and equitable planning, the urban (re)construction taking place now can integrate the latest climate solutions while also making our cities and towns better places to live and provide all with a higher quality of life. Fundamental to this achievement is protecting and more effectively using the services that nature provides human society. Nature-based solutions to climate change can’t address all our climate adaptation and mitigation challenges, but the data are strong that the more we can protect and enhance biodiversity and ecosystem function, the more benefits we can accrue in flood reduction, urban cooling, and air- and water-quality protection.

A key question is whether or not we can make such significant changes. Peering back into our own recent history, we find lots of stories of how we have done so. In a soon-to-be-published book, Cities and Environmental Change: From Crisis to Transformation, I document many examples of how seemingly overwhelming urban environmental crises were addressed through innovation. For example, by the mid-1950s air pollution had become a significant health and economic issue in the greater Los Angeles region. Within a decade transformative new air-pollution science, stakeholder coalitions, and governance institutions had been created and put into practice.

On a grand scale, the modernization of cities—while far from perfect—brought significant advances in drinking-water supply, sanitation, electrification, mass public transit, and recreation in many places. However, these developments were uneven, and today many cities, particularly in the Global South, are growing without the necessary infrastructure to adequately support the local population. Climate-resilient development is an opportunity to reduce or even eliminate these discrepancies.

The convergence of global climate change, rapid urbanization, and growing demands for economic and social equity create both an immediate imperative for action, and a rare opportunity to transform the present and create a better future. Successful solutions to past urban environmental crises can give us insights into how to best seize this opportunity: They show the importance of a flexible response where lived experiences, and the needs of multiple stakeholders are considered in policymaking.

Furthermore, we know that solutions should focus on securing the needed knowledge, financing, and decision-making capacity in advance, and being prepared to act when a window opens. Shocks like massive floods and disease outbreaks can become tipping points and bring attention to issues; but if emergent policies are to be effective and provide long-lasting solutions, they must also address underlying societal conditions, such as inequity and lack of trust in those in power due to a history of being cut out of the decision-making process.

Already, the world is full of small-scale climate-action success stories and other experiments that are making a difference. The historical evidence shows that to rapidly scale these up, we need to better monitor and evaluate these examples, bring in people and institutions from all levels of government, tap the incentive motives of the private sector, and address the concerns of those opposed to change. Even as the global community is failing the test of meeting the 1.5°C threshold, we have other resources to bring into the fight, and many of them are embedded in the history and culture of places and how we have addressed our past environmental crises.



source https://time.com/6565044/earth-2-point-0-climate-change/

Families of Hostages Held in Gaza Storm Israel’s Parliament Meeting Demanding Deal for Release

APTOPIX Israel Palestinians

JERUSALEM — Dozens of family members of hostages held by Hamas stormed a committee meeting in Israel’s parliament Monday, demanding a deal to win their loved ones’ release, as European foreign ministers joined growing international calls for Israel to negotiate on the creation of a Palestinian state after the war.

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The developments showed the increasing pressure on Israeli Prime Minister Benjamin Netanyahu, who has dug in on both fronts. He has insisted to the Israeli public that pursuing the devastating offensive in Gaza is the only way to bring the hostages home. At the same time, he has rejected the United States’ vision for a postwar resolution, saying he will never allow a Palestinian state.

The dispute over Gaza’s future — as the war rages with no end in sight — pits Israel against its top ally, the United States, as well as much of the international community. It also poses a major obstacle to any plans for postwar governance or reconstruction of the coastal territory, large parts of which have been left unlivable by Israeli bombardment.

In the most direct comments yet from Saudi Arabia, the kingdom’s top diplomat said it will not normalize relations with Israel or contribute to Gaza’s reconstruction without a credible path to a Palestinian state.

Netanyahu has vowed to continue the offensive until “complete victory” over Hamas and to return all remaining hostages after the Oct. 7 rampage in southern Israel that triggered the war. In that attack, some 1,200 people were killed and Hamas and other militants abducted around 250 people.

But more than three months into the war, Israelis are increasingly divided on the question of whether it’s possible to do both.

Around 100 hostages were freed under a weeklong cease-fire deal in November in exchange for the release of Palestinians held in Israeli prisons. Around 130 remain captive, but a number have since been confirmed dead. Hamas has said it will free more captives only in exchange for an end to the war and the release of thousands of Palestinian prisoners. Netanyahu has ruled out such an agreement.

Anger has been growing among hostages’ families. Relatives of hostages, as well as other protesters, have set up a tent camp outside Netanyahu’s residence in Jerusalem and vowed to remain until a deal is reached to bring the rest of the captives home. Other protests have called for new elections.

On Monday, dozens of family members of the hostages stormed into a gathering of the Knesset’s finance committee, holding up signs and yelling, “You won’t sit here while they are dying there!”

“These are our children!” they shouted. “We can’t continue with any other agenda, we need to discuss only one thing right now!”

Some had to be physically restrained as they shouted at the lawmakers, and at least one person was escorted out. The meeting was briefly suspended but later reconvened.

Over 25,000 killed in Gaza

Israel’s offensive has killed at least 25,295 Palestinians in Gaza and wounded more than 60,000, according to the Gaza Health Ministry. The ministry does not distinguish between civilians and combatants but says around two-thirds of those killed were women and children.

Medics reported heavy fighting in the southern city of Khan Younis, saying dozens of dead and wounded people were brought to the city’s already overwhelmed Nasser Hospital. Families could be seen fleeing south, to areas already packed with hundreds of thousands of displaced people.

The Israeli military says it has killed around 9,000 militants, without providing evidence, and blames the high civilian death toll on Hamas because it positions fighters, tunnels and other militant infrastructure in dense residential areas.

Some 85% of Gaza’s 2.3 million people have fled their homes, seeking elusive shelter in the south as Israel continues to strike all parts of the besieged enclave. U.N. officials say 1 in 4 people in Gaza are starving as the fighting and Israeli restrictions hinder the delivery of humanitarian aid.

The war has also stoked tensions across the region, with Iran-backed groups in Lebanon, Syria, Iraq and Yemen attacking Israeli and U.S. targets.NETANYAHU UNDER MOUNTING PRESSURE

Natanyahu, whose popularity has plummeted since Oct. 7, faces pressure from the U.S. to shift to more precise military operations and do more to facilitate humanitarian aid into Gaza.

The United States is also pushing him on its vision for postwar Gaza, calling for a reformed Palestinian Authority to govern the territory and for negotiations to start on a two-state solution. The authority currently governs pockets of the Israeli-occupied West Bank and was ejected from Gaza in 2007 when Hamas took power.

But Netanyahu’s governing coalition is beholden to far-right parties that want to step up the offensive, encourage the “voluntary” emigration of hundreds of thousands of Palestinians from Gaza and re-establish Jewish settlements there. Netanyahu has rejected the entry of the Palestinian Authority to Gaza and ruled out any Palestinian state, saying it would endanger Israel.

At a meeting about the war Monday in Brussels, European Union foreign ministers added their voices to the calls for a Palestinian state, saying it was the only way to achieve peace.

French Foreign Affairs Minister Stephane Sejourne said Netanyahu’s rejection of statehood was “worrying. There will be a need for a Palestinian state with security guarantees for all.”

“Which are the other solutions they have in mind?” EU foreign policy chief Josep Borrell said of Israel. “To make all the Palestinians leave? To kill them off?”

The comments late Sunday by Saudi Arabia’s foreign minister, Prince Faisal bin Farhan, were notable because before the war, the U.S. had been trying to broker a landmark agreement in which Saudi Arabia would normalize relations with Israel. In September, Netanyahu said Israel was on “the cusp” of a deal.

In an interview with CNN, host Fareed Zakaria asked: “Are you saying unequivocally that if there is not a credible and irreversible path to a Palestinian state, there will not be normalization of relations between Saudi Arabia and Israel?”

“That’s the only way we’re going to get a benefit,” Prince Faisal replied. “So, yes.”

When asked if oil-rich Saudi Arabia would finance reconstruction in Gaza, he said, “As long as we’re able to find a pathway to a solution … then we can talk about anything.”

“But if we are just resetting to the status quo before Oct. 7, in a way that sets us up for another round of this, as we have seen in the past, we’re not interested in that conversation.”

The Palestinians seek a state that would include Gaza, the Israeli-occupied West Bank and annexed east Jerusalem, territories Israel captured in the 1967 Mideast war.

Israel views all of Jerusalem as its capital and the West Bank as the historical and biblical heartland of the Jewish people. It has built scores of settlements across both territories that are home to hundreds of thousands of Jewish settlers. Peace talks broke down nearly 15 years ago.



source https://time.com/6565067/israelo-hostage-families-storm-parliament/

Will AI Take Your Job? Maybe Not Just Yet, One Study Says

Will artificial intelligence take our jobs? If you listen to Silicon Valley executives talking about the capabilities of today’s cutting edge AI systems, you might think the answer is “yes, and soon.”

But a new paper published by MIT researchers suggests automation in the workforce might happen slower than you think.

The researchers at MIT’s computer science and artificial intelligence laboratory studied not only whether AI was able to perform a task, but also whether it made economic sense for firms to replace humans performing those tasks in the wider context of the labor market.

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They found that while computer vision AI is today capable of automating tasks that account for 1.6% of worker wages in the U.S. economy (excluding agriculture), only 23% of those wages (0.4% of the economy as a whole) would, at today’s costs, be cheaper for firms to automate instead of paying human workers. “Overall, our findings suggest that AI job displacement will be substantial, but also gradual—and therefore there is room for [government] policy and retraining to mitigate unemployment impacts,” the authors write.

Tasks like analyzing images from diagnostic equipment in a hospital, or examining trays to ensure they contain the right items, are given in the paper as examples of the kind of “vision tasks” that today’s AI could feasibly achieve. But tasks like these are often so fragmented, the authors argue, that it is uneconomical to automate them.

“Even though there is some change that is coming, there is also some time to adapt to it,” Neil Thompson, the study’s lead author, tells TIME. “It’s not going to happen so rapidly that everything is thrown into chaos right away.”

Unless it does. The study only focused on computer vision AI—systems that are able to recognize and categorize objects in images and videos—rather than more flexible systems like multimodal large language models, of which OpenAI’s GPT-4 is an example. A recent study from OpenAI estimated that 19% of U.S. workers could see 50% of their workplace tasks “impacted” by GPT-4 level systems—a far higher estimate than the MIT researchers’ study that focuses solely on computer vision. A crucial question for the economy in the age of AI will be whether the MIT study’s findings apply to more “general” AI tools—ones that promise to automate most forms of cognitive labor that can be done behind a computer screen.

The MIT researchers found it can be expensive for companies to “fine tune” computer vision systems to make them suited for a specific, specialized task. While such an investment may make economic sense for the largest companies, it is often not cheaper for a small outfit that could simply retain a trained worker who already performs the task well. This dynamic is a key reason, according to the MIT paper, that not all tasks AI is capable of doing today are also economically viable to replace humans in. (The paper, submitted to the journal Management Science, has not yet been peer-reviewed.)

But it’s unclear whether this dynamic will carry over to language tasks. To “fine tune” a computer vision model to, for example, distinguish specific types of medicine bottle from one another to a 99.9% degree of accuracy, you would need to collect large quantities of labeled images of different medicines, which can be a costly and cumbersome process (even if low-wage workers in impoverished countries were drafted in to do it on the cheap). You would then have to pay the significant computing costs of fine-tuning an AI model on that large store of data.

Read More: OpenAI Used Kenyan Workers on Less Than $2 Per Hour to Make ChatGPT Less Toxic

On the other hand, fine-tuning a cutting-edge language model to carry out a specific task can simply be a matter of giving it a detailed list of written rules. An OpenAI study from August last year found that GPT-4 was able to effectively carry out the task of content moderation on digital platforms after being fine-tuned using a detailed policy document and just a few labeled examples. Those findings suggest that large language models can be applied to a wide range of economic tasks far more quickly, and cheaply, than computer vision models.  

Fine-tuning for GPT-4 is still in a restricted beta mode, as OpenAI works to mitigate the significant safety challenges this level of customizability can present. But as OpenAI and its competitors begin allowing customers to fine-tune their most advanced models, the economy may begin to see levels of automation, or augmentation, that progress faster than the MIT study predicts.

“It is certainly plausible that customizing large language models may be easier than customizing computer vision systems and that this could lead to more adoption in the economy,” Thompson tells TIME. But, “so long as a small engineering team is needed to integrate the system into the company’s workflow, costs are still restrictive.”



source https://time.com/6565026/ai-job-replacement-mit-study/

2024年1月21日 星期日

An Unexpected Encounter At Davos Inspired My Call to Action For the Israeli Hostages

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Something unusual and profound happened in Davos this year. I expected dynamic conversations on artificial intelligence, debates about global politics, and meetings with business and government leaders. True to form, those activities featured prominently during my time at the World Economic Forum’s annual meeting. However, there was one encounter I did not expect to have: a heart-wrenching discussion with four extraordinarily courageous Israeli women.

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Two of these individuals were themselves hostages in Gaza, the other two have loved ones still being held captive by Hamas. In an arena of power and influence, it was these humble and strong women who imparted upon me the greatest sense of urgency. They spoke as powerfully as any business titan or world leader. And then some.

Noam Peri grew up in Kibbutz Nir-Oz, a small, tight-knit farming village. Her 79-year-old father, an admirer of the arts, a dedicated family man, and a steadfast peace advocate, remains a hostage.

Nili Margalit was taken on October 7. As a nurse, she tended to the wounded among her fellow hostages. What she lacked in medical supplies, she made up for with her compassion. Now free, her heart remains with those who are still in captivity.

Moran Stela Yanai, a jewelry maker, attended the Supernova music festival to sell her wares and enjoy the camaraderie. Hobbling on an injured leg, a physical reminder of her ordeal, she bravely spoke through tears of the treatment she suffered at the hands of her captors.

Rachel Goldberg is the mother of Hersh, a 23-year-old man whose arm was blown off by grenades before he was taken hostage. She wears a homemade tag with the number of days Hersh has been held captive. When we met, that number stood at 103.

These women deserve to be heard. We must heed their call for the release of the hostages. All of us. They must have our active support, and not just for a day, but until all of the captives have been freed. There should be nothing political about this issue. This is about human decency. The hostages are in dire conditions—reports of food shortages, torture, and sexual abuse. As such, every minute counts.

I say this while recognizing the broader spectrum of sorrow and loss in this conflict, including the innocent families in Gaza, caught in the crossfire, who endure their own tragedies. What binds us as people should urge us to look beyond borders and divisions. This is call to action for our common humanity.

It is our moral duty, as global citizens, to take the necessary steps to help the hostages. To start, we can learn more about them. They are real, innocent people facing unspeakable cruelty.

As citizens of the digital generation, we have the opportunity to raise public awareness, calling for the release of all hostages using the hashtag #BringThemHomeNow. We must rally around those elected officials who are advocating to bring the hostages home. By participating in the democratic process—sending an email or calling our senators, representatives, and the White House—we can give a voice to the hostages.

Join Ms. Goldberg, just as I did in Davos, by wearing a piece of tape on your shirt, counting the number of days that the 136 hostages are still not home. As the devoted mom told me, it reminds the world of the inhumanity at play.

As a healthcare leader, I have a responsibility to stress the urgent need for hostages to gain access to medication. International organizations need unfettered access to assess the conditions of the hostages, so that they can receive the necessary care. Supporting the families of hostages, and of course, the hostages themselves, does not end when they are brought home; mental health services must be made available to those in need, for as long as necessary. 

The conditions for a return to calm and stability should be our priority. We owe it to the hostages to hold tightly to the hope that eventual peace, and the end to this cycle of violence, is within reach.

I will sign off with a question: Imagine if it were your loved one being held captive. What would you do?



source https://time.com/6564827/israeli-hostages-call-to-action-davos-encounter/

من هشت سال گروگان ایران بودم. آیا دوستانم از بمباران اسرائیل جان سالم به در بردند؟

Read this story in English here نمازی گروگان سابق آمریکایی در ایران است و اکنون عضو هیئت مشاوران ابتکار آزادی برای زندانیان سیاسی در...